Article
Role of GSTM1 and GSTT1 polymorphism: susceptibility to oral submucous fibrosis in the North Indian population.
Oncology - 1 Jan 2010
Agrawal Deepa, Gupta Shalini, Agarwal Deepti, Gupta Om Prakash, Agarwal Mohit
Abstract excerpt
Molecular epidemiological studies have provided evidence that individual susceptibility to cancer is mediated by both genetic and environmental factors. Several allelic variants of polymorphic glutathione s-transferases (GSTs) show impaired enzyme activity and are suspected to increase the host's susceptibility to various cancers. To determine the association of GST variants with the risk of oral submucous...
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