Article
Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.
Annals of surgical oncology - 1 Nov 2012
Nordgård Oddmund, Oltedal Satu, Aasprong Ole Gunnar, Søreide Jon Arne, Søreide Kjetil, Tjensvoll Kjersti, Gilje Bjørnar, Heikkilä Reino, Guriby Marianne, Lothe Ragnhild A, Smaaland Rune, Kørner Hartwig
Abstract excerpt
PURPOSE: To investigate the prognostic value of occult metastases detected by quantitative measurements of candidate biomarkers in sentinel lymph nodes (SLNs) from patients curatively resected for colon cancer. METHODS: Resection specimens from consecutive patients undergoing surgery for localized colon cancer were subjected to ex vivo SLN mapping. SLNs were examined for the presence of metastases by routine...
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