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Article

Two-stage fermentation process for enhanced mannitol production using Candida magnoliae mutant R9.

Bioprocess and biosystems engineering - 1 Feb 2013

Savergave Laxman S, Gadre Ramchandra V, Vaidya Bhalchandra K, Jogdand Vitthal V

Abstract excerpt

Mutants of Candida magnoliae NCIM 3470 were generated by treatment of ultra-violet radiations, ethyl methyl sulphonate and N-methyl-N'-nitro-N-nitrosoguanidine. Mutants with higher reductase activity were screened by means of 2,3,5-triphenyl tetrazolium chloride agar plate assay. Among the screened mutants, the mutant R9 produced maximum mannitol (i.e. 46 g l(-1)) in liquid fermentation medium containing 250 g...

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PMID: 22752246
DOI: 10.1007/s00449-012-0775-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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