Article
UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts.
Mechanisms of ageing and development - 1 Aug 2012
Dato Serena, Soerensen Mette, Montesanto Alberto, Lagani Vincenzo, Passarino Giuseppe, Christensen Kaare, Christiansen Lene
Abstract excerpt
An efficient uncoupling process is generally considered to have a protective effect on the aging muscle by slowing down its age-related decay. Genetic polymorphisms in the Uncoupling Protein 3 (UCP3) gene, whose product is mainly expressed in skeletal muscle, were suggested to be associated with hand grip (HG) performances in elderly populations. Considering the population specificity of the quality of aging, we...
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