Article
THE ROLE OF HEREDITARY PREDISPOSITION (POLYMORPHIC MARKERS OF GLUTATHIONE-S-TRANSFERASE, CATALASE, ENDOTHELIAL NITROGEN OXIDE SYNTHASE GENES) AND SOME ADVERSE ENVIRONMENTAL FACTORS IN THE DEVELOPMENT OF BRONCHO-OBSTRUCTIVE PATHOLOGY IN CHILDREN LIVING IN RADIOACTIVELY CONTAMINATED AREAS.
Problemy radiatsiinoi medytsyny ta radiobiolohii - 1 Dec 2023
Kolpakov I Ye, Vdovenko V Yu, Zyhalo V M, Kondrashova V G, Chobotko H M, Raichuk L A, Leonovych O S
Abstract excerpt
OBJECTIVE: summarizing the results of many years of research by the authors on the influence of gene polymorphisms encoding xenobiotic biotransformation enzymes (GSTТ1, GSTM1, GSTР1), antioxidant protection (С^262Т of the catalase gene), endothelial nitric oxide synthase (4a/4b VNTR polymorphism of the eNOS gene), and some environmental factors on the occurrence of broncho-obstructive disorders and the...
Topics
- Child
- Humans
- Polymorphism, Genetic
- Nitric Oxide Synthase Type III
- Catalase
- Minisatellite Repeats
- Genetic Predisposition to Disease
- Asthma
- Nitrogen Oxides
- Glutathione