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Article

EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms

1 Jun 2012

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22733077
DOI: 10.1038/leu.2012.146

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Related research

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EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasmsPMID 22733077Read ↗

Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasmsSemantic proximity Read ↗

<i>Eed</i> controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crestSemantic proximity Read ↗

Polycomb complexes in normal and malignant hematopoiesisSemantic proximity Read ↗

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformationSemantic proximity Read ↗

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.Semantic proximity Read ↗

Clarifying the Impact of Polycomb Complex Component Disruption in Human CancersSemantic proximity Read ↗

Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations.Semantic proximity Read ↗

Roles of Polycomb gene <i>EED</i> in pathogenesis and prognosis of acute myeloid leukemia and diffuse large B cell lymphomaSemantic proximity Read ↗

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent mannerSemantic proximity Read ↗

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cellsSemantic proximity Read ↗

Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutationsSemantic proximity Read ↗

Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.Semantic proximity Read ↗

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