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Article

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

23 Jun 2014

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Share to Acute Myeloid Leukemia Research
Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24953053
DOI: 10.1038/ncomms5177

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Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformationPMID 24953053Read ↗

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent mannerSemantic proximity Read ↗

EZH2 in Myeloid Malignancies.Semantic proximity Read ↗

Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoringSemantic proximity Read ↗

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Molecular characterization of EZH2 mutant patients with myelodysplastic/myeloproliferative neoplasms.Semantic proximity Read ↗

Telomere Dysfunction Drives Aberrant Hematopoietic Differentiation and Myelodysplastic SyndromeSemantic proximity Read ↗

Epigenetics in myelodysplastic syndromesSemantic proximity Read ↗

Epigenetic dysregulation in myelodysplastic syndromes.Semantic proximity Read ↗

Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations.Semantic proximity Read ↗

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.Semantic proximity Read ↗

Cellular carcinogenesis in preleukemic conditions:drivers and defenses.Semantic proximity Read ↗

IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progressionSemantic proximity Read ↗

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