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Article

Identifying mutation regions for closely related individuals without a known pedigree.

BMC bioinformatics - 25 Jun 2012

Cui Wenjuan, Wang Lusheng

Abstract excerpt

BACKGROUND: Linkage analysis is the first step in the search for a disease gene. Linkage studies have facilitated the identification of several hundred human genes that can harbor mutations leading to a disease phenotype. In this paper, we study a very important case, where the sampled individuals are closely related, but the pedigree is not given. This situation happens very often when the individuals share a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22731852
DOI: 10.1186/1471-2105-13-146
PMCID: PMC3507658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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