Article
Autoregulation of Musashi1 mRNA translation during Xenopus oocyte maturation.
Molecular reproduction and development - 1 Aug 2012
Arumugam Karthik, Macnicol Melanie C, Macnicol Angus M
Abstract excerpt
The mRNA translational control protein, Musashi, plays a critical role in cell fate determination through sequence-specific interactions with select target mRNAs. In proliferating stem cells, Musashi exerts repression of target mRNAs to promote cell cycle progression. During stem cell differentiation, Musashi target mRNAs are de-repressed and translated. Recently, we have reported an obligatory requirement for...
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