Article
A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.
PloS one - 1 Jan 2013
Chew Ting Gang, Peaston Anne, Lim Ai Khim, Lorthongpanich Chanchao, Knowles Barbara B, Solter Davor
Abstract excerpt
Mammalian oocytes are arrested at prophase I of meiosis, and resume meiosis prior to ovulation. Coordination of meiotic arrest and resumption is partly dependent on the post-transcriptional regulation of maternal transcripts. Here, we report that, SPINDLIN1 (SPIN1), a maternal protein containing Tudor-like domains, interacts with a known mRNA-binding protein SERBP1, and is involved in regulating maternal...
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