Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Donor Satellite Cell Engraftment Is SignificantlyAugmented When the Host Niche Is Preserved and Endogenous Satellite Cells Are Incapacitated

22 Jun 2012

Abstract excerpt

Stem cell transplantation is already in clinical practice for certain genetic diseases and is a promising therapy for dystrophic muscle. We used the mdx mouse model of Duchenne muscular dystrophy to investigate the effect of the host satellite cell niche on the contribution of donor muscle stem cells (satellite cells) to muscle regeneration. We found that incapacitation of the host satellite cells and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Muscle Physiology and Disorders
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22730231
DOI: 10.1002/stem.1158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Donor Satellite Cell Engraftment Is SignificantlyAugmented When the Host Niche Is Preserved and Endogenous Satellite Cells Are IncapacitatedPMID 22730231Read ↗

Satellite cells from dystrophic muscle retain regenerative capacitySemantic proximity Read ↗

Loss of stem cell regenerative capacity within aged nichesSemantic proximity Read ↗

Stem Cell Review Series: Aging of the skeletal muscle stem cell nicheSemantic proximity Read ↗

“The Social Network” and Muscular Dystrophies: The Lesson Learnt about the Niche Environment as a Target for Therapeutic StrategiesSemantic proximity Read ↗

Are Human and Mouse Satellite Cells Really the Same?Semantic proximity Read ↗

The ins and outs of muscle stem cell aging.Semantic proximity Read ↗

Direct effects of the pathogenic mutation on satellite cell function in muscular dystrophy.Semantic proximity Read ↗

Altered muscle niche contributes to myogenic deficit in the D2- <i>mdx</i> model of severe DMDSemantic proximity Read ↗

Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle.Semantic proximity Read ↗

Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophySemantic proximity Read ↗

Unacylated Ghrelin Enhances Satellite Cell Function and Relieves the Dystrophic Phenotype in Duchenne Muscular Dystrophy mdx Model.Semantic proximity Read ↗

Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.