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Stem Cell Review Series: Aging of the skeletal muscle stem cell niche

5 May 2008

Abstract excerpt

Declining stem cell function during aging contributes to impaired tissue function. Muscle-specific stem cells ('satellite cells') are responsible for generating new muscle in response to injury in the adult. However, aged muscle displays a significant reduction in regenerative abilities and an increased susceptibility to age-related pathologies. This review describes components of the satellite cell niche and...

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PMID: 18462272
DOI: 10.1111/j.1474-9726.2008.00399.x

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