Article
The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19.
Expert opinion on drug metabolism & toxicology - 1 Jan 2015
Yang Yao, Lewis Joshua P, Hulot Jean-Sébastien, Scott Stuart A
Abstract excerpt
INTRODUCTION: Aspirin, clopidogrel, prasugrel and ticagrelor are antiplatelet agents for the prevention of ischemic events in patients with acute coronary syndromes (ACS), percutaneous coronary intervention (PCI) and other indications. Variability in response is observed to different degrees with these agents, which can translate to increased risks for adverse cardiovascular events. As such, potential...
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