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Article

UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection.

PloS one - 1 Jan 2012

Crane Meredith J, Gaddi Pamela J, Salazar-Mather Thais P

Abstract excerpt

Antiviral defense in the liver during acute infection with the hepatotropic virus murine cytomegalovirus (MCMV) involves complex cytokine and cellular interactions. However, the mechanism of viral sensing in the liver that promotes these cytokine and cellular responses has remained unclear. Studies here were undertaken to investigate the role of nucleic acid-sensing Toll-like receptors (TLRs) in initiating...

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Source

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Identifiers

PMID: 22723955
DOI: 10.1371/journal.pone.0039161
PMCID: PMC3377622

Genes

TLR3
TLR7
TLR9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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