Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deregulation of a Hox Protein Regulatory Network Spanning Prostate Cancer Initiation and Progression

22 Jun 2012

Abstract excerpt

PURPOSE: The aberrant activity of developmental pathways in prostate cancer may provide significant insight into predicting tumor initiation and progression, as well as identifying novel therapeutic targets. To this end, despite shared androgen-dependence and functional similarities to the prostate gland, seminal vesicle cancer is exceptionally rare. EXPERIMENTAL DESIGN: We conducted genomic pathway analyses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clusterin in disease pathology
Share to Prostate Cancer Diagnosis and Treatment
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22723371
DOI: 10.1158/1078-0432.ccr-12-0373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deregulation of a Hox Protein Regulatory Network Spanning Prostate Cancer Initiation and ProgressionPMID 22723371Read ↗

MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic DiseaseSemantic proximity Read ↗

HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directionsSemantic proximity Read ↗

MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycansSemantic proximity Read ↗

Conserved Gene Expression Programs Integrate Mammalian Prostate Development and TumorigenesisSemantic proximity Read ↗

HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancerSemantic proximity Read ↗

The predictive significance of chromobox family members in prostate cancer in humansSemantic proximity Read ↗

MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activitySemantic proximity Read ↗

MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activitySemantic proximity Read ↗

Importance of HOX genes in normal prostate gland formation, prostate cancer development and its early detectionSemantic proximity Read ↗

Iroquois homeobox 4 (IRX4) derived micropeptide promotes prostate cancer progression and chemoresistance through Wnt signalling dysregulationSemantic proximity Read ↗

Clinical and Functional Analyses of an African-ancestry Gain-of-function HOXB13 Variant Implicated in Aggressive Prostate CancerSemantic proximity Read ↗

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.