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Article

Roles of Hsp90 in Candida albicans morphogenesis and virulence

1 Jul 2023

Abstract excerpt

Hsp90 is a conserved molecular chaperone that facilitates the folding and function of hundreds of client proteins, many of which serve as core hubs of signal transduction networks. Hsp90 has a critical role in virulence of the opportunistic fungal pathogen Candida albicans, which exists as a natural commensal of the human microbiota and is a leading cause of invasive fungal infections, particularly in...

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PMID: 37399670
DOI: 10.1016/j.mib.2023.102351

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