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Article

Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells.

PLoS genetics - 1 Jan 2012

Bose Tania, Lee Kenneth K, Lu Shuai, Xu Baoshan, Harris Bethany, Slaughter Brian, Unruh Jay, Garrett Alexander, McDowell William, Box Andrew, Li Hua, Peak Allison, Ramachandran Sree, Seidel Chris, Gerton Jennifer L

Abstract excerpt

Cohesin is a protein complex known for its essential role in chromosome segregation. However, cohesin and associated factors have additional functions in transcription, DNA damage repair, and chromosome condensation. The human cohesinopathy diseases are thought to stem not from defects in chromosome segregation but from gene expression. The role of cohesin in gene expression is not well understood. We used...

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Identifiers

PMID: 22719263
DOI: 10.1371/journal.pgen.1002749
PMCID: PMC3375231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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