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Article

KRAS mutations as prognostic and predictive markers in non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2013

Martin Petra, Leighl Natasha B, Tsao Ming-Sound, Shepherd Frances A

Abstract excerpt

A greater understanding of non-small-cell lung cancer at a molecular level has led to the identification of an increasing number of driver mutations. Extensive research of the KRAS gene as well as specific mutations has established its role in tumorigenesis. Nevertheless, the role of KRAS oncogene in non-small-cell lung cancer remains unclear. Recent studies indicated that mutant KRAS could be predictive of lack...

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Identifiers

PMID: 23524403
DOI: 10.1097/JTO.0b013e318283d958

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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