Article
The clinical relevance of KRAS gene mutation in non-small-cell lung cancer.
Current opinion in oncology - 1 Mar 2014
Tímár József
Abstract excerpt
PURPOSE OF REVIEW: There are conflicting data on the potential prognostic and predictive role of mutant KRAS in non-small-cell lung cancer (NSCLC). RECENT FINDINGS: KRAS is the most frequently mutated oncogene in lung adenocarcinoma patients of non-Asian ethnicity. Novel data also revealed that allelic variants of mutant KRAS are different concerning their biochemistry, which may influence their prognostic and...
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