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Article

Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells.

Journal of cellular biochemistry - 1 Dec 2012

Chen Yulin, Li Dan, Wang Dapeng, Liu Xuefeng, Yin Ning, Song Yongmei, Lu Shih Hsin, Ju Zhenyu, Zhan Qimin

Abstract excerpt

Accumulating evidence indicates cancer stem cells (CSCs) possess the capability to resist DNA-damage induced cell death, whereas the mechanism is largely unknown. Here we show that cell cycle status and DNA damage response (DDR) in CSCs probably contribute to their survival in genotoxic insults....

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Source

Identifiers

PMID: 22711554
DOI: 10.1002/jcb.24228

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22711554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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