Article
Molecular profiling of conjunctival epithelial side-population stem cells: atypical cell surface markers and sources of a slow-cycling phenotype.
Investigative ophthalmology & visual science - 1 Sept 2009
Akinci M A Murat, Turner Helen, Taveras Maria, Barash Alex, Wang Zheng, Reinach Peter, Wolosin J Mario
Abstract excerpt
PURPOSE: Side-population (SP) cells isolated from limbal and conjunctival epithelia derive from cells that are slow cycling in vivo, a known feature of tissue stem cells. The purpose of this study was to define the molecular signature of the conjunctival SP cells and identify markers and signaling pathways associated with the phenotype of these cells. METHODS: Overnight cultures of freshly isolated human...
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