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Article

TOMM40, APOE, and APOC1 in primary progressive aphasia and frontotemporal dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2012

Seripa Davide, Bizzarro Alessandra, Pilotto Andrea, Palmieri Orazio, Panza Francesco, D'Onofrio Grazia, Gravina Carolina, Archetti Silvana, Daniele Antonio, Borroni Barbara, Padovani Alessandro, Masullo Carlo

Abstract excerpt

The aim of this study was to investigate the apolipoprotein E (APOE) chromosomal region in frontotemporal lobar degeneration (FTLD), and in particular in primary progressive aphasia (PPA) and the behavioral variant frontotemporal dementia (bvFTD). To this aim, we selected three single-nucleotide polymorphisms (SNPs) rs2075650 and rs157590 (TOMM40), and rs1064725 (APOC1), representative of the linkage...

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Share to Aged, 80 and over
Share to Aphasia, Primary Progressive
Share to Apolipoprotein C-I
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Share to Frontotemporal Dementia
Share to Membrane Transport Proteins
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Source

Identifiers

PMID: 22710912
DOI: 10.3233/JAD-2012-120403

Genes

APOE
TOMM40
APOC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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