Article
Specific interleukin-1 gene polymorphisms in Turkish patients with Behçet's disease.
Experimental dermatology - 1 Feb 2005
Coskun Mesut, Bacanli Ali, Sallakci Nilgun, Alpsoy Erkan, Yavuzer Ugur, Yegin Olcay
Abstract excerpt
Genetic factors that predispose individuals to Behçet's disease (BD) are considered to play important roles in the development of the disease. The pro-inflammatory cytokine interleukin-1 (IL-1) has been implicated in the pathogenesis of BD. Our aim was to determine a possible association of specific polymorphisms of IL-1alpha, IL-1beta, and IL-1 receptor antagonist genes with susceptibility for BD. We genotyped...
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