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Article

Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease.

Molecular vision - 1 Jan 2012

Karakus Nevin, Yigit Serbulent, Kalkan Goknur, Rustemoglu Aydin, Inanir Ahmet, Gul Ulker, Pancar Gunseli Sefika, Akkanet Songul, Ates Omer

Abstract excerpt

PURPOSE: Behcet's disease (BD) is a multisystemic immunoinflammatory disorder characterized by mucocutaneous, ocular, vascular, and central nervous system manifestations. The common methylene tetrahydrofolate reductase (MTHFR) gene C677T mutation is a known risk factor for thrombosis. The aim of this study was to investigate the MTHFR gene C677 mutation in patients with BD and evaluate if there was an association...

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Source

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Identifiers

PMID: 22773907
PMCID: PMC3388981

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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