Article
ERAP1 polymorphisms interactions and their association with Behçet's disease susceptibly: Application of Model-Based Multifactor Dimension Reduction Algorithm (MB-MDR).
PloS one - 1 Jan 2020
Riahi Parisa, Kazemnejad Anoshirvan, Mostafaei Shayan, Meguro Akira, Mizuki Nobuhisa, Ashraf-Ganjouei Amir, Javinani Ali, Faezi Seyedeh Tahereh, Shahram Farhad, Mahmoudi Mahdi
Abstract excerpt
BACKGROUND: Behçet's disease (BD) is a chronic multi-systemic vasculitis with a considerable prevalence in Asian countries. There are many genes associated with a higher risk of developing BD, one of which is endoplasmic reticulum aminopeptidase-1 (ERAP1). In this study, we aimed to investigate the interactions of ERAP1 single nucleotide polymorphisms (SNPs) using a novel data mining method called Model-based...
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