Article
Population screening of single-nucleotide polymorphisms exemplified by analysis of 8000 alleles.
Journal of biomolecular screening - 1 Dec 2002
Ekstrøm Per Olaf, Bjørheim Jens, Gaudernack Gustav, Giercksky Karl-Erik
Abstract excerpt
The authors describe a method in which the population frequency of single-nucleotide polymorphisms (SNPs) can be efficiently detected and their allele frequencies accurately measured. Selected SNPs in TNFbeta, IL-4, and CTLA-4 were used to demonstrate the method. Blood from 4000 individuals was p...
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