Article
Association of the CD14 gene -159C polymorphism with progression of IgA nephropathy.
Journal of medical genetics - 1 Feb 2003
Yoon H-J, Shin J H, Yang S H, Chae D-W, Kim H, Lee D-S, Kim H L, Kim S, Lee J S, Kim Y S
Abstract excerpt
The risk factors associated with the progression of IgA nephropathy (IgAN), the most common form of glomerulonephritis, are unclear. It has been suggested that CD14 signalling in response to various microbes affects the natural history of chronic inflammatory conditions. It has been hypothesised that variants in the promoter region of the CD14 gene might alter the expression of CD14, and this in turn could...
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