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Article

A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma.

Cancer cell - 12 Jun 2012

De Vito Claudio, Riggi Nicolo, Cornaz Sandrine, Suvà Mario-Luca, Baumer Karine, Provero Paolo, Stamenkovic Ivan

Abstract excerpt

We have recently demonstrated that human pediatric mesenchymal stem cells can be reprogrammed toward a Ewing sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSCs is shared by embryonic stem...

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Share to Embryonic Stem Cells
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Share to Mice, Inbred NOD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Experimental

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Share to Sarcoma, Ewing

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Source

Identifiers

PMID: 22698405
DOI: 10.1016/j.ccr.2012.04.023

Genes

TARBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22698405-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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