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Article

miRNAs regulate stem cell self-renewal and differentiation

1 Jan 2012

Abstract excerpt

Stem cells undergo symmetric and asymmetric divisions to generate differentiated cells and more stem cells. The balance between self-renewal and differentiation of stem cells is controlled by transcription factors, epigenetic regulatory networks, and microRNAs (miRNAs). Herein the miRNA involvement in the regulation of stem cell self-renewal and differentiation is summarized. miRNA contribution to malignancy...

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Identifiers

PMID: 23056008
DOI: 10.3389/fgene.2012.00191

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