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Article

Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients.

Carcinogenesis - 1 Sept 2012

Xiong Donghai, Li Guangming, Li Kezhen, Xu Qinzi, Pan Zhongjie, Ding Feng, Vedell Peter, Liu Pengyuan, Cui Peng, Hua Xing, Jiang Hui, Yin Yuxin, Zhu Ze, Li Xiaomian, Zhang Bin, Ma Ding, Wang Yian, You Ming

Abstract excerpt

Lung cancer has become the top killer among malignant tumors in China and is significantly associated with somatic genetic alterations. We performed exome sequencing of 14 non-small cell lung carcinomas (NSCLCs) with matched adjacent normal lung tissues extracted from Chinese patients. In additio...

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Source

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Identifiers

PMID: 22696596
DOI: 10.1093/carcin/bgs210
PMCID: PMC3514907

Genes

EGFR
KRAS
MXRA5
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22696596-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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