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Article

The role of the factor V Leiden mutation in osteonecrosis of the hip.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Sept 2013

Glueck Charles J, Freiberg Richard A, Boriel Gail, Khan Zia, Brar Amanpreet, Padda Jagjit, Wang Ping

Abstract excerpt

We examined the hypothesis that the factor V Leiden (FVL) and G20101A prothrombin gene mutations are commonly associated with hip osteonecrosis. We prospectively evaluated 244 consecutively referred adults with osteonecrosis (ON), 161 idiopathic and 83 secondary. Cases (n = 244) did not differ from 104 normal controls by race. Of the 244 patients, 23 (9.4%) were FVL heterozygotes versus 2 of 104 controls (1.9%),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22696591
DOI: 10.1177/1076029612449901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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