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Article

Association of Vitamin D Pathway Genetic Variation and Thyroid Cancer

28 Jul 2019

Abstract excerpt

Vitamin D is mostly known for its role in bone and calcium metabolism. However, studies have suggested that it also has inhibitory effects on tumor development and progression. Genetic variants close to genes that encode crucial enzymes for the synthesis (DHCR7 rs12785878), metabolism (CYP2R1 rs2060793) and degradation (CYP24A1 rs6013897) of vitamin D have been associated with serum levels of vitamin D. The aim...

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PMID: 31357732
DOI: 10.3390/genes10080572

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