Article
DNA methylation in schizophrenia subjects: gender and MTHFR 677C/T genotype differences.
Epigenomics - 1 Jun 2012
Burghardt Kyle J, Pilsner J Richard, Bly Michael J, Ellingrod Vicki L
Abstract excerpt
AIM: In schizophrenia, metabolic syndrome incidence is double that of the general population, with women having a higher incidence. Pharmacogenetically regulated folic acid may be related to this risk. DNA methylation and metabolic syndrome within this group has not been previously studied. METHODS: Metabolic syndrome was evaluated with fasting laboratory measurements, and dietary and lifestyle assessments....
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