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Article

Lack of genetic association of the UCHL1 gene with Alzheimer's disease and Parkinson's disease with dementia.

Dementia and geriatric cognitive disorders - 1 Jan 2012

Shibata Nobuto, Motoi Yumiko, Tomiyama Hiroyuki, Ohnuma Tohru, Kuerban Bolati, Tomson Katrin, Komatsu Miwa, Hattori Nobutaka, Arai Heii

Abstract excerpt

BACKGROUND/AIMS: Several candidate genes were suggested to modify the susceptibility to both Alzheimer's disease (AD) and Parkinson's disease (PD). Symptoms of dementia are found in approximately 30% of PD patients. Both apolipoprotein E (APO E) and ubiquitin carboxyl-terminal esterase L1 (UCHL1) are neuropathogenic proteins for both diseases. The aim of this study was to investigate whether polymorphisms of both...

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Source

Identifiers

PMID: 22688354
DOI: 10.1159/000339357

Genes

UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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