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Article

Clonal B cells of HCV-associated mixed cryoglobulinemia patients contain exhausted marginal zone-like and CD21 low cells overexpressing Stra13.

European journal of immunology - 1 Jun 2012

Visentini Marcella, Cagliuso Maria, Conti Valentina, Carbonari Maurizio, Cibati Marina, Siciliano Giulia, Cristofoletti Cristina, Russo Giandomenico, Casato Milvia, Fiorilli Massimo

Abstract excerpt

A clonal population of B cells expressing a V(H) 1-69-encoded idiotype accumulates in hepatitis C virus (HCV) associated mixed cryoglobulinemia (MC). These cells are phenotypically heterogeneous, resembling either typical marginal zone (MZ) B cells (IgM(+) IgD(+) CD27(+) CD21(+) ) or the exhauste...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22678901
DOI: 10.1002/eji.201142313

Genes

BCR
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22678901-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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