Article
[Polymorphisms of FEM1A gene in patients with polycystic ovary syndrome].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2012
Lin Yuan, Sun Yan
Abstract excerpt
OBJECTIVE: To assess the association between FEM1A gene polymorphisms and polycystic ovary syndrome (PCOS) in Chinese Han patients. METHODS: DNA sequencing was utilized to determine the genotypes of rs12460989 and rs8111933 loci of FEM1A gene in 120 PCOS patients and 155 healthy controls. Association between above polymorphisms and hyperandrogenism and insulin resistance (IR) was assessed. RESULTS: Genotypes TT,...
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