Article
[Case-control based study between polymorphisms in the adiponectin gene and polycystic ovary syndrome].
Zhonghua fu chan ke za zhi - 1 Nov 2015
Zhang Wenjuan, Wu Xingguo, Ding Mingde, Yu Xinyan, Liu Guanghai, Shi Yuhua
Abstract excerpt
OBJECTIVE: To investigate the frequeney of four single nucleotide polymorphism (SNP) sites (rs17300539, rs12495941, rs2241766 and rs1501299) of adiponectin gene (ADIPOQ) and to elucidate its role in the pathogenesis of polycystic ovary syndrome (PCOS). METHODS: A total of 207 women with PCOS and 192 controls were recruited. Four ml whole-blood samples were collected in tubes containing ethylene diamine...
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