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Article

Genetic factors for choroidal neovascularization associated with high myopia.

Investigative ophthalmology & visual science - 27 Jul 2012

Leveziel Nicolas, Yu Yi, Reynolds Robyn, Tai Albert, Meng Weihua, Caillaux Violaine, Calvas Patrick, Rosner Bernard, Malecaze François, Souied Eric H, Seddon Johanna M

Abstract excerpt

PURPOSE: Nonsyndromic high myopia, defined by a refractive error greater than -6 diopters (D), is associated with an increased risk of macular choroidal neovascularization (CNV), a vision-threatening complication. The aim of this study was to investigate whether genetic factors associated with age-related macular degeneration (AMD) are related to myopic CNV. METHODS: We conducted a case-control study, including...

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Source

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Identifiers

PMID: 22678500
DOI: 10.1167/iovs.12-9538
PMCID: PMC3410690

Genes

CFI
APOE
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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