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Article

Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility.

Molecular vision - 1 Jan 2012

Tran-Viet Khanh-Nhat, St Germain Elizabeth, Soler Vincent, Powell Caldwell, Lim Sing-Hui, Klemm Thomas, Saw Seang Mei, Young Terri L

Abstract excerpt

PURPOSE: Myopia, or nearsightedness, is highly prevalent in Asian countries and is considered a serious public health issue globally. High-grade myopia can predispose individuals to myopic maculopathy, premature cataracts, retinal detachment, and glaucoma. A recent study implicated zinc finger protein 644 isoform 1 (ZNF644) variants with non-syndromic high-grade myopia in a Chinese-Asian population. Herein we...

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Source

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Identifiers

PMID: 22539872
PMCID: PMC3335780

Variants

rs12117237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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