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Article

Evaluation of pigment epithelium-derived factor and complement factor I polymorphisms as a cause of choroidal neovascularization in highly myopic eyes.

Investigative ophthalmology & visual science - 19 Jun 2013

Miyake Masahiro, Yamashiro Kenji, Nakanishi Hideo, Nakata Isao, Akagi-Kurashige Yumiko, Kumagai Kyoko, Oishi Maho, Tsujikawa Akitaka, Moriyama Muka, Ohno-Matsui Kyoko, Mochizuki Manabu, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: A case-control study in a relatively large cohort of highly myopic patients was conducted to explore the genetic background of the occurrence of choroidal neovascularization (CNV) secondary to high myopia. METHODS: We evaluated three single nucleotide polymorphisms (SNPS) from two candidate genes: pigment epithelium-derived factor (PEDF) and complement factor I (CFI). The SNPs were selected based on...

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PMID: 23722394
DOI: 10.1167/iovs.13-12280

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CFI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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