Article
The prostate cancer risk locus at 10q11 is associated with DNA repair capacity.
DNA repair - 1 Aug 2012
Rinckleb Antje E, Surowy Harald M, Luedeke Manuel, Varga Dominic, Schrader Mark, Hoegel Josef, Vogel Walther, Maier Christiane
Abstract excerpt
Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that mildly predict prostate cancer risk. These SNPs are local tagging markers for causal gene alterations. Consideration of candidate genes in the tagged regions would be facilitated by additional information on the particular pathomechanisms which contribute to the observed risk increase. In this study we test...
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