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Article

Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers

7 Jun 2012

Abstract excerpt

BACKGROUND: Mucus hypersecretion contributes to the morbidity and mortality of smoking-related lung diseases, especially chronic obstructive pulmonary disease (COPD), which starts in the small airways. Despite progress in animal studies, the genes and their expression pattern involved in mucus production and secretion in human airway epithelium are not well understood. We hypothesized that comparison of the...

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PMID: 22676183
DOI: 10.1186/1755-8794-5-21

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