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Article

Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus.

PloS one - 1 Jan 2012

James Michael A, Wen Weidong, Wang Yian, Byers Lauren A, Heymach John V, Coombes Kevin R, Girard Luc, Minna John, You Ming

Abstract excerpt

Cleft Lip and Palate Transmembrane Protein 1-Like (CLPTM1L), resides in a region of chromosome 5 for which copy number gain has been found to be the most frequent genetic event in the early stages of non-small cell lung cancer (NSCLC). This locus has been found by multiple genome wide association studies to be associated with lung cancer in both smokers and non-smokers. CLPTM1L has been identified as an...

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Identifiers

PMID: 22675468
DOI: 10.1371/journal.pone.0036116
PMCID: PMC3366984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus.PMID 22675468Read ↗

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