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Article

Molecular epidemiology of Aspergillus fumigatus isolates harboring the TR34/L98H azole resistance mechanism.

Journal of clinical microbiology - 1 Aug 2012

Camps Simone M T, Rijs Antonius J M M, Klaassen Corné H W, Meis Jacques F, O'Gorman Céline M, Dyer Paul S, Melchers Willem J G, Verweij Paul E

Abstract excerpt

A rapid emergence of azole resistance has been observed in Aspergillus fumigatus in The Netherlands over the past decade. The dominant resistance mechanism appears to be of environmental origin and involves the TR(34)/L98H mutations in cyp51A. This resistance mechanism is now also increasingly being found in other countries. Therefore, genetic markers were used to gain more insights into the origin and spread of...

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Identifiers

PMID: 22675126
DOI: 10.1128/JCM.00335-12
PMCID: PMC3421523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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