Article
Environmental study of azole-resistant Aspergillus fumigatus with TR34/L98H mutations in the cyp51A gene in Iran.
Mycoses - 1 Nov 2013
Badali Hamid, Vaezi Afsane, Haghani Iman, Yazdanparast Seyed A, Hedayati Mohammad T, Mousavi Bita, Ansari Saham, Hagen Ferry, Meis Jacques F, Chowdhary Anuradha
Abstract excerpt
Azole resistance in Aspergillus is emerging in European and Asian countries. As azoles are mainstay of therapy in the management of aspergillosis, azole resistance has serious implications in patient management. We report the emergence of resistance to triazoles in environmental Aspergillus fumigatus isolates in Iran. The TR34/L98H mutation was the only resistance mechanism. Overall 3.3% of the A. fumigatus...
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