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Article

Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2012

Huang Chengdong, Li Guangtao, Lennarz William J

Abstract excerpt

The hexameric protein p97, a very abundant type II AAA ATPase (ATPase associated with various cellular activities), is involved in a diverse range of cellular functions. During its ATPase cycle p97 functions as an ATP motor, converting the chemical energy released upon hydrolysis of ATP to ADP into mechanical work, which is then directed toward the proteins that serve as substrates. A key question in this process...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22675116
DOI: 10.1073/pnas.1205853109
PMCID: PMC3382474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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