Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the drug transporter gene ABCB1 predict side effects of treatment with cabergoline in patients with PRL adenomas.

European journal of endocrinology - 1 Sept 2012

Athanasoulia A P, Sievers C, Ising M, Brockhaus A C, Yassouridis A, Stalla G K, Uhr M

Abstract excerpt

INTRODUCTION: Treatment with dopamine agonists in patients with prolactin (PRL) adenomas and Parkinson's disease is associated with central side effects. Central side effects may depend on a substance's ability to pass the blood-brain barrier, which can be actively controlled by transporter molecules such as the P-glycoprotein (P-gp) encoded by the ABCB1 gene. MATERIALS AND METHODS: We aimed to determine whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to ATP Binding Cassette Transporter, Subfamily D, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Fatigue

Share to Headache

Share to Mice, Knockout

Share to Pituitary Neoplasms

Share to Predictive Value of Tests

Source

Identifiers

PMID: 22672924
DOI: 10.1530/EJE-12-0198

Genes

ABCB1
PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the drug transporter gene ABCB1 predict side effects of treatment with cabergoline in patients with PRL adenomas.PMID 22672924Read ↗

Association of a polymorphism in the ABCB1 gene with Parkinson's disease.Semantic proximity Read ↗

The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.Semantic proximity Read ↗

Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers.Semantic proximity Read ↗

Cabergoline and prolactinomas: lack of association between DRD2 polymorphisms and response to treatment.Semantic proximity Read ↗

Pharmacogenetics of D2 dopamine receptor gene in prolactin-secreting pituitary adenomas.Semantic proximity Read ↗

ABCB1 variants and sex affect serotonin transporter occupancy in the brainSemantic proximity Read ↗

Prolactinomas resistant to standard doses of cabergoline: a multicenter study of 92 patients.Semantic proximity Read ↗

Influence of ABCB1 Genotype in Collies on the Pharmacokinetics and Pharmacodynamics of Loperamide in a Dose-Escalation Study.Semantic proximity Read ↗

ABCB1 c.2677G>T variation is associated with adverse reactions of OROS-methylphenidate in children and adolescents with ADHD.Semantic proximity Read ↗

Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel.Semantic proximity Read ↗

Do CYP3A and ABCB1 genotypes influence the plasma concentration and clinical outcome of donepezil treatment?Semantic proximity Read ↗

Dopamine D2 receptor gene polymorphisms and response to cabergoline therapy in patients with prolactin-secreting pituitary adenomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.