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Article

Determinants contributing to claudin ion channel formation.

Annals of the New York Academy of Sciences - 1 Jun 2012

Veshnyakova Anna, Krug Susanne M, Mueller Sebastian L, Piontek Jörg, Protze Jonas, Fromm Michael, Krause Gerd

Abstract excerpt

Pore-forming properties of claudins (Cld) are likely defined by residues of their first extracellular loop (ECL1). Detailed mechanisms are unclear. MDCK cells overexpressing FLAG-Cld-1 wild-type and mutants were characterized by transepithelial resistance (TER) and ion permeability measurements....

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Identifiers

PMID: 22671588
DOI: 10.1111/j.1749-6632.2012.06566.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22671588-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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