Article
Population subdivision and adaptation in asexual populations of Saccharomyces cerevisiae.
Evolution; international journal of organic evolution - 1 Jun 2012
Kryazhimskiy Sergey, Rice Daniel P, Desai Michael M
Abstract excerpt
Population subdivision limits competition between individuals, which can have a profound effect on adaptation. Subdivided populations maintain more genetic diversity at any given time compared to well-mixed populations, and thus "explore" larger parts of the genotype space. At the same time, beneficial mutations take longer to spread in such populations, and thus subdivided populations do not "exploit" discovered...
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