Article
8q24 Cancer risk allele associated with major metastatic risk in inflammatory breast cancer.
PloS one - 1 Jan 2012
Bertucci François, Lagarde Arnaud, Ferrari Anthony, Finetti Pascal, Charafe-Jauffret Emmanuelle, Van Laere Steven, Adelaide José, Viens Patrice, Thomas Gilles, Birnbaum Daniel, Olschwang Sylviane
Abstract excerpt
BACKGROUND: Association studies have identified low penetrance alleles that participate to the risk of cancer development. The 8q24 chromosomal region contains several such loci involved in various cancers that have been recently studied for their propensity to influence the clinical outcome of prostate cancer. We investigated here two 8q24 breast and colon cancer risk alleles in the close vicinity of the MYC...
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